CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
C5 BAC-transgenic mice identify complement factor 5 as genetic risk factor that modifies liver fibrosis
DOI 10.1055/s-2005-920087
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Autor:innenS Hillebrandt, H Keppeler, H Wasmuth, S Matern, T Sauerbruch, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Unknown host genetic factors play a role in the progression of hepatic fibrosis. Recently we identified murine gene loci (Hfib loci) that confer susceptibility to hepatic fibrosis in an experimental intercross between fibrosis-susceptible (BALB/cJ) and resistant (A/J) inbred strains of mice. The Hfib2 locus on proximal chromosome 2 shows a highly significant association with hepatic collagen deposition and his…
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Zitierempfehlung
S Hillebrandt, H Keppeler, H Wasmuth, S Matern, T Sauerbruch, F Lammert (2006) C5 BAC-transgenic mice identify complement factor 5 as genetic risk factor that modifies liver fibrosis. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920087
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