CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
TAp73/ΔNp73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma
DOI 10.1055/s-2005-920108
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Autor:innenE Schulze Schleithoff, AE Sayan, AF Koch, C Pieper, O Gressner, G Melino, PH Krammer, A Tannapfel, W Stremmel, M Müller
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
p73, a p53 family protein, has significant homology to p53. Unlike p53, the expression of p73 is regulated by two different promoters resulting in proteins with opposite functions: the full-length transcriptionally active TAp73 and the dominant negative p73 (ΔNp73). We investigated the downstream mechanisms by which TAp73ß and ΔNp73 regulate apoptosis. TAp73ß transactivated the CD95 gene via the p53-binding site in…
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Zitierempfehlung
E Schulze Schleithoff, AE Sayan, AF Koch, C Pieper, O Gressner, G Melino, PH Krammer, A Tannapfel, W Stremmel, M Müller (2006) TAp73/ΔNp73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920108
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