CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The α5β1 fibronectin receptor sensitizes carcinoma cells to Galectin–1 mediated anoikis
DOI 10.1055/s-2005-920110
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Autor:innenH Sanchez-Ruderisch, K Detjen, M Buchholz, M Welzel, S André, A Wimmel, B Wiedenmann, G Gress, HJ Gabius, S Rosewicz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Resistance to anoikis, an apoptosis program initiated by loss of contact to the extracellular matrix, is a hallmark of transformed epithelial cells. In previous studies, we could restore anoikis in Capan–1 human pancreatic cancer cells by restitution of p16 via mechanisms that required the induction of the fibronectin receptor α5β1. To identify potential mediators in the p16-dependent pathway that induces anoikis, w…
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Zitierempfehlung
H Sanchez-Ruderisch, K Detjen, M Buchholz, M Welzel, S André, A Wimmel, B Wiedenmann, G Gress, HJ Gabius, S Rosewicz (2006) The α5β1 fibronectin receptor sensitizes carcinoma cells to Galectin–1 mediated anoikis. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920110
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