CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hypermethylation of the Prospero-related gene (PROX1) in intra- and extrahepatic cholangiocarcinomas
DOI 10.1055/s-2005-920122
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Lärm, J Macho, R Dammann, HJ Holzhausen, WG Ballhausen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: The transcription factor Prospero-related gene 1 (PROX1) is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm. Directed hepatocyte migration into the septum transversum during liver development requires PROX1. Intriguingly, inactivation of PROX1 caused abnormal cellular proliferation via down-regulated expression of the cell-cycle inhibitors CDKN1B and CDKN1C, i.e…
Zitieren
Zitierempfehlung
A Lärm, J Macho, R Dammann, HJ Holzhausen, WG Ballhausen (2006) Hypermethylation of the Prospero-related gene (PROX1) in intra- and extrahepatic cholangiocarcinomas. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920122
Mit CareLit weiterarbeiten