CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The insulin-like growth factor receptor is a promising target for innovative treatment approaches of hepatocellular cancer
DOI 10.1055/s-2005-920140
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Autor:innenM Höpfner, A Hüther, V Baradari, D Schuppan, H Scherübl
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aims: Hepatocellular carcinoma (HCC) is one of the most common cancer-related causes of death worldwide. Due to very poor 5-year-survival new therapeutic approaches are uregently needed. Most HCCs express insulin-like growth factors and their receptors (IGFR). As IGF–1R-mediated signaling promotes survival, oncogenic transformation and tumor growth and spread, it represents a potential target for innova…
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Zitierempfehlung
M Höpfner, A Hüther, V Baradari, D Schuppan, H Scherübl (2006) The insulin-like growth factor receptor is a promising target for innovative treatment approaches of hepatocellular cancer. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920140
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