CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The focal adhesion kinase FAK, but not PYK2, plays a central role for growth factor signaling in HepG2-hepatoma cells
DOI 10.1055/s-2005-920142
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Pace, J Kluwe, A Tulun, M Bläker, A de Weerth
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
BKG: The structurally related focal adhesion kinases FAK and PYK2 are involved in key signal transduction pathways in normal and malignant tissues. In spite of their structural homology, they have distinct roles in key cellular events such as cell adhesion, regulation of the cell cycle and apoptosis. In contrast to PYK2, FAK promotes cell-survival and proliferation. Hepatocellular carcinoma is one of the most common…
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Zitierempfehlung
A Pace, J Kluwe, A Tulun, M Bläker, A de Weerth (2006) The focal adhesion kinase FAK, but not PYK2, plays a central role for growth factor signaling in HepG2-hepatoma cells. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920142
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