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Phosphoramidon, a novel matrix metalloproteinase inhibitor, inhibits significantly tumor growth independently of the application route (intraperitoneal [i.p.] versus intravenous [i.v.]) in a rat model of peritoneal carcinomatosis

A Hribaschek, F Meyer, K Ridwelski, P Habermann, H Lippert · Zeitschrift für Gastroenterologie · Ausgabe 04/2006

DOI 10.1055/s-2005-920173

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Autor:innenA Hribaschek, F Meyer, K Ridwelski, P Habermann, H Lippert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben

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Introduction: Occurrence of peritoneal carcinomatosis remains still an unsolved problem in gastrointestinal cancer. Over the last years, novel antineoplastic substances such as matrix metalloproteinase (MMP) inhibitors have been investigated in animal models to achieve a decrease of tumor growth. The aim of the study was to determine whether i) Phosphoramidon, an MMP inhibitor, can prevent or diminish i.p. tumor gro…

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A Hribaschek, F Meyer, K Ridwelski, P Habermann, H Lippert (2006) Phosphoramidon, a novel matrix metalloproteinase inhibitor, inhibits significantly tumor growth independently of the application route (intraperitoneal [i.p.] versus intravenous [i.v.]) in a rat model of peritoneal carcinomatosis. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920173

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