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Transcription of the exon 1f/i multi promoter cluster of neuronal nitric oxide synthase is dynamically upregulated by retinoic acid in a cell specific manner

K Schönhofer, F Nagl, G Schneider, B Seidler, HD Allescher, RM Schmid, D Saur · Zeitschrift für Gastroenterologie · Ausgabe 04/2006

DOI 10.1055/s-2005-920190

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Autor:innenK Schönhofer, F Nagl, G Schneider, B Seidler, HD Allescher, RM Schmid, D Saur
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Changes of neuronal NO-synthase (nNOS) expression have been linked to several human gastrointestinal disorders such as achalasia, gastroparesis and IHPS. 9 distinct first exons (1a–1i) of the nNOS gene, driven by separate promoters, exists, showing site specific expression profiles in the human gastrointestinal tract. We have previously shown that nNOS exon 1c expression is significantly decreased in patients with I…

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K Schönhofer, F Nagl, G Schneider, B Seidler, HD Allescher, RM Schmid, D Saur (2006) Transcription of the exon 1f/i multi promoter cluster of neuronal nitric oxide synthase is dynamically upregulated by retinoic acid in a cell specific manner. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920190

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