CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
In vivo activity of humanized monoclonal anti-EGFR antibody EMD 72000 in combination with gemcitabine on growth of primary pancreatic tumors and metastases in an orthotopic nude mouse model
DOI 10.1055/s-2005-920385
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Nachweis in CareLit
Autor:innenO Mantell, C Amendt, M Yezhelyev, H Starck, M Guba, KW Jauch, CJ Bruns
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Deregulation of epidermal growth factor receptor (EGFR) pathways contributes to the progression of a wide range of cancers, and the EGFR is an attractive therapeutic target. The humanized EGFR-specific monoclonal antibody EMD 72000 has shown potent inhibitory activity in preclinical experiments and is under investigation in clinical studies. Material and Methods: Using the human L3.6pl pancreatic cance…
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Zitierempfehlung
O Mantell, C Amendt, M Yezhelyev, H Starck, M Guba, KW Jauch, CJ Bruns (2006) In vivo activity of humanized monoclonal anti-EGFR antibody EMD 72000 in combination with gemcitabine on growth of primary pancreatic tumors and metastases in an orthotopic nude mouse model. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920385
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