CareLit · DOI-Nachweis · Zentralblatt für Gynäkologie
Other cancer types besides breast and ovarian cancer in 266 families with a proven BRCA1/2 mutation or a high probability for an autosomal dominant gene
DOI 10.1055/s-2005-921002
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Bosse, K Weinhold, K Rhiem, V Hübbel, P Mallmann, B Wappenschmidt, RK Schmutzler
ZeitschriftZentralblatt für Gynäkologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objective: BRCA1/2 mutations go along with a significantly elevated lifetime risk for breast and ovarian cancer reaching up to 80% and 50% respectively. Both genes are supposed to participate in a common pathway that is involved in the control of DNA damage repair. This fundamental role rises the question whether mutations in these genes predispose towards cancerous lesions in other tissues. Patients: Our data were…
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Zitierempfehlung
K Bosse, K Weinhold, K Rhiem, V Hübbel, P Mallmann, B Wappenschmidt, RK Schmutzler (2005) Other cancer types besides breast and ovarian cancer in 266 families with a proven BRCA1/2 mutation or a high probability for an autosomal dominant gene. Zentralblatt für Gynäkologie (10). https://doi.org/10.1055/s-2005-921002
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