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Correlation between protein and RNA tissue concentration of invasion factors urokinase-type plasminogen activator (uPA) and its inhibitor, plasminongen activator inhibitor type 1 (PAI-1)

M Bader, C Thomssen, E Laczynska, M Gehrmann, M Munnes, F Jänicke, V Müller · Zentralblatt für Gynäkologie · Ausgabe 10/2005

DOI 10.1055/s-2005-921021

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Autor:innenM Bader, C Thomssen, E Laczynska, M Gehrmann, M Munnes, F Jänicke, V Müller
ZeitschriftZentralblatt für Gynäkologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben

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Introduction: Protein concentration of uPA and its inhibitor PAI-1 are prognostic factors in lymph-node negative breast cancer. Analysis of uPA and PAI-1 mRNA by quantitative real time PCR or array based nucleic acid detection platforms could be alternatives which use less tissue. Methods: The concentration of uPA and PAI-1 protein was measured by ELISA (American Diagnostica) in 151 tumor samples. In addition, RNA o…

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M Bader, C Thomssen, E Laczynska, M Gehrmann, M Munnes, F Jänicke, V Müller (2005) Correlation between protein and RNA tissue concentration of invasion factors urokinase-type plasminogen activator (uPA) and its inhibitor, plasminongen activator inhibitor type 1 (PAI-1). Zentralblatt für Gynäkologie (10). https://doi.org/10.1055/s-2005-921021

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