CareLit · DOI-Nachweis · Pneumologie
Toll-like receptor (TLR) 4 Asp299Gly and Thr399Ile polymorphisms are associated with a chronic progressive course of pulmonary sarcoidosis
DOI 10.1055/s-2005-925493
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Pabst, G Baumgarten, A Stremmel, M Lennarz, P Knuefermann, A Gillissen, H Vetter, C Grohé
ZeitschriftPneumologie
Ausgabe01/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The aetiology of sarcoidosis, an inflammatory granulomatous multisystem disorder, is unclear. It is supposed to be the product of an unknown exogenous antigenic stimulus and an endogenous genetic susceptibility. Toll-like receptors (TLR) are signal molecules essential for the cellular response to bacterial cell wall components. Lipopolysaccharide (LPS), for example, binds to TLR 4. Two different polymorp…
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Zitierempfehlung
S Pabst, G Baumgarten, A Stremmel, M Lennarz, P Knuefermann, A Gillissen, H Vetter, C Grohé (2006) Toll-like receptor (TLR) 4 Asp299Gly and Thr399Ile polymorphisms are associated with a chronic progressive course of pulmonary sarcoidosis. Pneumologie (01). https://doi.org/10.1055/s-2005-925493
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