CareLit · DOI-Nachweis · Pneumologie
Role of urokinase type plasminogen (uPA) in pulmonary vascular remodeling in a murine model of hypoxia induced pulmonary hypertension
DOI 10.1055/s-2005-925514
Bibliografische Angaben
Nachweis in CareLit
Autor:innenBK Dahal, RT Schermuly, P Markat, C Ruppert, R Schmidt, M Korfei, W Seeger, N Weissman, A Guenther
ZeitschriftPneumologie
Ausgabe01/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: uPA is a serine proteinase involved in intravascular as well as extravascular proteolytic processes. Among the plasminogen activator inhibitors (PAIs), PAI-1 is the principle physiological inhibitor. A balance between fibrinolytic and antifibrinolytic pathways is essential for vascular physiology and alterations of the fibrinolytic system have been reported in patients with primary pulmonary hypertension…
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Zitierempfehlung
BK Dahal, RT Schermuly, P Markat, C Ruppert, R Schmidt, M Korfei, W Seeger, N Weissman, A Guenther (2006) Role of urokinase type plasminogen (uPA) in pulmonary vascular remodeling in a murine model of hypoxia induced pulmonary hypertension. Pneumologie (01). https://doi.org/10.1055/s-2005-925514
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