CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The Endocannabinoid 2-Arachidonoyl Glycerol Induces Apoptosis in Primary Hepatic Stellate Cells and Is Upregulated During Hepatic Fibrogenesis
DOI 10.1055/s-2006-931625
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Autor:innenSV Siegmund, T Qian, J Harvey-White, G Kunos, DA Brenner, RF Schwabe
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: The endogenous cannabinoid 2-arachidonoyl glycerol (2-AG) is a lipid mediator that blocks proliferation and induces cell death in many cell types. AIM: To determine 2-AG levels during hepatic fibrogenesis and evaluate its effect on primary hepatic stellate cells (HSCs) and hepatocytes. Methods: Primary rat hepatocytes and rat and human HSCs were isolated from healthy human or rat liver by collagenase perfusion…
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Zitierempfehlung
SV Siegmund, T Qian, J Harvey-White, G Kunos, DA Brenner, RF Schwabe (2006) The Endocannabinoid 2-Arachidonoyl Glycerol Induces Apoptosis in Primary Hepatic Stellate Cells and Is Upregulated During Hepatic Fibrogenesis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2006-931625
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