CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Ski/SnoN as negative regulators of certain TGF-β signaling pathways in liver cells
DOI 10.1055/s-2006-931632
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Autor:innenL Ciuclan, K Breitkopf, P Godoy, E Wiercinska, MV Singer, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
TGF-β1 is a critical factor promotingstellate cell transdifferentiation into myofibroblasts, with subsequentshift of balance in the extracellular matrix degradation toward synthesis. Since hepatocytes are the predominant liver cell type and are responsive to TGF-β, they may also actively contribute to fibrogenesis. Aims: To study the TGF-β1 pathway in isolated hepatocytes and hepatocyte-derived cell lines, with spec…
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Zitierempfehlung
L Ciuclan, K Breitkopf, P Godoy, E Wiercinska, MV Singer, S Dooley (2006) Ski/SnoN as negative regulators of certain TGF-β signaling pathways in liver cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2006-931632
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