CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Expression and TGF-beta modulation of connective tissue growth factor (CTGF) in hepatic stellate cells and hepatocytes
DOI 10.1055/s-2006-931639
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Autor:innenAM Gressner, B Lahme, O Gressner, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: CTGF, a heparin binding 38 kd cysteine-rich peptide is well known as a secreted, TGF-β regulated down-stream TGF-β effector molecule, which is strongly expressed in fibrotic liver tissue, especially in fibrogenic hepatic stellate cells (HSC) and myofibroblasts (MFB). CTGF is suggested to play an important role as a positive trap for TGF-β by facilitating its receptor binding and as a negative trap for BM…
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Zitierempfehlung
AM Gressner, B Lahme, O Gressner, R Weiskirchen (2006) Expression and TGF-beta modulation of connective tissue growth factor (CTGF) in hepatic stellate cells and hepatocytes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2006-931639
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