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Transdifferentiation-dependent expression of distinct C5a-receptors C5R1 and C5L2 in cultured hepatic stellate cells and their response to C5a-ligand
DOI 10.1055/s-2006-931640
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Autor:innenO Gressner, S Hillebrandt, R Weiskirchen, H Keppeler, G Hack, T Sauerbruch, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: Recently we reported that the complement factor 5 (C5) is a susceptibility gene for hepatic fibrogenesis in mice and humans (Hillebrandt S et al. Nat Genet 2005). However, the underlying fibrogenic mechanisms of C5 have yet to be defined. Therefore, we initiated the present study with primary cultures of rat hepatic stellate cells (HSC) to analyze the expression of the bona fide receptor C5R1 for the sma…
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Zitierempfehlung
O Gressner, S Hillebrandt, R Weiskirchen, H Keppeler, G Hack, T Sauerbruch, F Lammert (2006) Transdifferentiation-dependent expression of distinct C5a-receptors C5R1 and C5L2 in cultured hepatic stellate cells and their response to C5a-ligand. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2006-931640
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