CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
TGF-β induced upregulation of CRP2 and SRF in activated hepatic stellate cells–Involvement in smooth muscle gene expression during liver fibrogenesis?
DOI 10.1055/s-2006-931646
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Autor:innenJ Herrmann, U Haas, E Van de Leur, A Gressner, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Activation of hepatic stellate cells (HSC), mainly triggert by transforming growth factor-β (TGF-β), is a key event in liver fibrogenesis accompanied by modulations of gene expression e.g. upregulation of contractile proteins known as markers of smooth muscle cell (SMC) differentiation. In SMCs the marker genes are principally regulated by binding of serum response factor (SRF) to unique sequences in t…
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Zitierempfehlung
J Herrmann, U Haas, E Van de Leur, A Gressner, R Weiskirchen (2006) TGF-β induced upregulation of CRP2 and SRF in activated hepatic stellate cells–Involvement in smooth muscle gene expression during liver fibrogenesis?. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2006-931646
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