CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis
DOI 10.1055/s-2006-931751
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Nachweis in CareLit
Autor:innenM Mühlbauer, M Fleck, T Weiss, M Froh, C Schütz, C Blank, J Schölmerich, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
B7-H1 (PD-L1) is a B7-family member that binds to programmed death–1 (PD–1). Recently, deficiency of PD-L1 has been demonstrated to result in accelerated hepatocyte damage in experimental autoimmune hepatitis, and PD-L1 was suggested to play a critical role in regulating T-cell homeostasis. Absence of PD–1 enhanced proliferation of T cells in adenovirus-infected livers and resulted in a rapid clearance of the virus.…
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Zitierempfehlung
M Mühlbauer, M Fleck, T Weiss, M Froh, C Schütz, C Blank, J Schölmerich, C Hellerbrand (2006) PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2006-931751
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