CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Differential sensitization of hepatocytes by inhibitors of histone deacetylases against death receptor-induced apoptosis
DOI 10.1055/s-2006-931766
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Autor:innenM Weiller, G Dünstl, A Wendel, G Künstle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Preclinical and clinical studies suggest that inhibition of histone/protein deacetylation by targeting histone deacetylases (HDACs) represents a novel approach in cancer therapy [1]. However, only recently it became evident that HDAC inhibitors by themselves do not only induce apoptosis but also render cells sensitive to death receptor agonists, i.e. TNF, TRAIL, and CD95 ligand (CD95L), respectively [2, 3]. Fo…
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Zitierempfehlung
M Weiller, G Dünstl, A Wendel, G Künstle (2006) Differential sensitization of hepatocytes by inhibitors of histone deacetylases against death receptor-induced apoptosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2006-931766
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