Legionella pathogenicity

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Legionella pneumophila is the most frequent species among the Legionellaceae. In the environment it infects protozoa. When transmitted to humans it can cause influenza-like infection called Pontiac-fever or pneumonia, especially in immunocompromised patients. In cases of human infection it enters alveolar macrophages by coiling or conventional phagocytosis and replicates within a so called replicative phagosom that…

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