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Streptococcus Pneumoniae-induced P38 MAPK and NF-kB dependent COX-2 expression in human lung epithelium

N Dje P'Guessan, S Hippenstiel, M Etouem, J Zahlten, W Beermann, D Lindner, B Opitz, M Witzenrath, S Rosseau, N Suttorp, B Schmeck · Pneumologie · Ausgabe 02/2006

DOI 10.1055/s-2006-932722

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Autor:innenN Dje P'Guessan, S Hippenstiel, M Etouem, J Zahlten, W Beermann, D Lindner, B Opitz, M Witzenrath, S Rosseau, N Suttorp, B Schmeck
ZeitschriftPneumologie
Ausgabe02/2006
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: S. pneumoniae is a major cause of community-acquired pneumonia and death due to infectious diseases in industrialized countries. Lung airway and alveolar epithelial cells comprise an important barrier against airborne pathogens. Cyclooxygenase (COX) derived prostaglandins like prostaglandin E2 (PGE2) are considered as important regulators of lung function. Herein we tested the hypothesis that pneumococ…

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N Dje P'Guessan, S Hippenstiel, M Etouem, J Zahlten, W Beermann, D Lindner, B Opitz, M Witzenrath, S Rosseau, N Suttorp, B Schmeck (2006) Streptococcus Pneumoniae-induced P38 MAPK and NF-kB dependent COX-2 expression in human lung epithelium. Pneumologie (02). https://doi.org/10.1055/s-2006-932722

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