CareLit · DOI-Nachweis · Pneumologie
Legionella pneumophila induced IL-8 expression in human pulmonary epithelium by MAP kinases, NF-kB and histone modifications
DOI 10.1055/s-2006-932727
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Nachweis in CareLit
Autor:innenB Schmeck, N Dje P'Guessan, J Lorenz, B Opitz, B Brell, A Flieger, M Witzenrath, S Rosseau, N Suttorp, S Hippenstiel
ZeitschriftPneumologie
Ausgabe02/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: L. pneumophila induced severe pneumonia in humans due to the inhalation of Legionella-contaminated water droplets. In this study we tested the hypothesis that Legionella induced pro-inflammatory activation of pulmonary epithelial cells and analyzed involved signalling pathways. Methods: human lung epithelial cells (A549), Bioplex-assay, IL-8-ELISA, Western blot, reportergen-assay, chromatin-immunopreci…
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Zitierempfehlung
B Schmeck, N Dje P'Guessan, J Lorenz, B Opitz, B Brell, A Flieger, M Witzenrath, S Rosseau, N Suttorp, S Hippenstiel (2006) Legionella pneumophila induced IL-8 expression in human pulmonary epithelium by MAP kinases, NF-kB and histone modifications. Pneumologie (02). https://doi.org/10.1055/s-2006-932727
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