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Characterization of Matrix Metalloproteinase (MMP) expression and activity in the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF)

T Nkyimbeng, C Ruppert, P Markart, M Korfei, R Schmidt, W Seeger, A Günther · Pneumologie · Ausgabe 04/2006

DOI 10.1055/s-2006-933753

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Autor:innenT Nkyimbeng, C Ruppert, P Markart, M Korfei, R Schmidt, W Seeger, A Günther
ZeitschriftPneumologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Matrix metalloproteinases (MMPs) are inducible zinc-dependent, secreted or cell surface endopeptidases that are centrally involved in extracellular matrix turnover. An imbalance of MMPs and their inhibitors (TIMPs) in the lung was recently suggested to contribute to the pathogenesis of interstitial lung diseases such as Idiopathic Pulmonary Fibrosis (IPF). Objective: In the present study we investigated…

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Zitierempfehlung

T Nkyimbeng, C Ruppert, P Markart, M Korfei, R Schmidt, W Seeger, A Günther (2006) Characterization of Matrix Metalloproteinase (MMP) expression and activity in the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF). Pneumologie (04). https://doi.org/10.1055/s-2006-933753

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