CareLit · DOI-Nachweis · Pneumologie
Acute lung injury induced by the pyrrolizidine alkaloid monocrotaline in mice
DOI 10.1055/s-2006-934026
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR Dumitrascu, S Köbrich, H Traupe, E Dony, S Pullamsetti, R Savai, A Samidurai, N Weissmann, A Ghofrani, F Grimminger, W Seeger, R Schermuly
ZeitschriftPneumologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common and lethal conditions. The mortality rate of ALI/ARDS depends on the underlying cause, varying from 60% for sepsis-induced ALI/ARDS. The aim of this study was to develop an animal model of ALI in mice employing monocrotaline (MCT). The MCT induces endothelial injury and pulmonary hypertension in rats. The proposed mechanism of action i…
Zitieren
Zitierempfehlung
R Dumitrascu, S Köbrich, H Traupe, E Dony, S Pullamsetti, R Savai, A Samidurai, N Weissmann, A Ghofrani, F Grimminger, W Seeger, R Schermuly (2006) Acute lung injury induced by the pyrrolizidine alkaloid monocrotaline in mice. Pneumologie (04). https://doi.org/10.1055/s-2006-934026
Mit CareLit weiterarbeiten