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Hybrid-primed lymphocytes and hybrid vaccination prevent tumor growth of lewis lung carcinoma in mice

S Rajkumar, R Schermuly, M Schneider, S Pullamsetti, F Grimminger, W Seeger, G Banat · Pneumologie · Ausgabe 04/2006

DOI 10.1055/s-2006-934032

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Autor:innenS Rajkumar, R Schermuly, M Schneider, S Pullamsetti, F Grimminger, W Seeger, G Banat
ZeitschriftPneumologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Dendritic cell (DC)-tumor cell hybrids are currently being evaluated as a novel anti-tumor vaccination strategy. We here explored in an animal model whether administration of DCs fused with poorly immunogenic carcinoma cells could elicit an anti-tumor response. Fusion of C57BL/6 mice bone marrow derived DCs with Lewis Lung Carcinoma (LLC1) cells resulted in around 50% fusion efficiency. Hybrid cells (HC) were used t…

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Zitierempfehlung

S Rajkumar, R Schermuly, M Schneider, S Pullamsetti, F Grimminger, W Seeger, G Banat (2006) Hybrid-primed lymphocytes and hybrid vaccination prevent tumor growth of lewis lung carcinoma in mice. Pneumologie (04). https://doi.org/10.1055/s-2006-934032

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