CareLit · DOI-Nachweis · Klinische Neurophysiologie
Expression of a glial potassium channel in the developing cerebellum and impact of its genetic inactivation on neuronal cell survival
DOI 10.1055/s-2006-939244
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Autor:innenC Neusch, M Kaiser, M Bähr, F Kirchhoff
ZeitschriftKlinische Neurophysiologie
Ausgabe03/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Objective: Glia cells may play a prominent role in degenerative cerebellar diseases such as Multiple System Atrophy or Spinocerebellar Ataxia. Genetic inactivation of a glial Kir channel subunit (Kir4.1, KCNJ10)) in mice leads to developmental CNS defects with ataxia and limb paralysis (Neusch et al., 2001). One important function of Kir4.1 is regulating the extracellular K+ concentration in neuronal active compartm…
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Zitierempfehlung
C Neusch, M Kaiser, M Bähr, F Kirchhoff (2006) Expression of a glial potassium channel in the developing cerebellum and impact of its genetic inactivation on neuronal cell survival. Klinische Neurophysiologie (03). https://doi.org/10.1055/s-2006-939244
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