CareLit · DOI-Nachweis · Zeitschrift für Geburtshilfe und Neonatologie
Latent TGF-beta1 associated with SP-A: Possible novel mechanism to regulate TGF-beta1 mediated inflammation and fibrosis in the lung
DOI 10.1055/s-2006-943152
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Kunzmann, JR Wright, W Steinhilber, BW Kramer, K Blaser, C Schmidt-Weber, C Speer
ZeitschriftZeitschrift für Geburtshilfe und Neonatologie
Ausgabe05/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Surfactant protein A (SP-A) and active transforming growth factor beta (TGF-beta) 1 have been shown to modulate the functions of various immune cells in the lung. TGF-beta1 is released by cells as latent, biologically inactive complexes. After an activation step TGF-beta1 signaling from the cell membrane to the nucleus is mediated through Smad2/3 proteins. The signaling pathway of SP-A is however unknown. The aim of…
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Zitierempfehlung
S Kunzmann, JR Wright, W Steinhilber, BW Kramer, K Blaser, C Schmidt-Weber, C Speer (2006) Latent TGF-beta1 associated with SP-A: Possible novel mechanism to regulate TGF-beta1 mediated inflammation and fibrosis in the lung. Zeitschrift für Geburtshilfe und Neonatologie (05). https://doi.org/10.1055/s-2006-943152
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