CareLit · DOI-Nachweis · Zeitschrift für Geburtshilfe und Neonatologie
No evidence for germ-line transmission following prenatal and early postnatal AAV-mediated gene delivery
DOI 10.1055/s-2006-943290
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Jakob, C Mühle, J Park, S Frank, S Waddington, H Schneider
ZeitschriftZeitschrift für Geburtshilfe und Neonatologie
Ausgabe05/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Recombinant adeno-associated viruses have been used successfully in a number of pre-clinical and clinical gene therapy studies. Since there is a broad consensus that gene therapy must not lead to germ-line transmission, the potential of such vectors for inadvertent gene transfer into germ cells deserves special attention. This applies in particular to pre- or perinatal vector application which has been c…
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Zitierempfehlung
M Jakob, C Mühle, J Park, S Frank, S Waddington, H Schneider (2006) No evidence for germ-line transmission following prenatal and early postnatal AAV-mediated gene delivery. Zeitschrift für Geburtshilfe und Neonatologie (05). https://doi.org/10.1055/s-2006-943290
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