CareLit · DOI-Nachweis · Zeitschrift für Geburtshilfe und Neonatologie
Evaluation of prenatal intra-amniotic LAMB3 gene delivery by adenoviral and AAV vectors in a mouse model of Herlitz junctional epidermolysis bullosa
DOI 10.1055/s-2006-943291
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Autor:innenC Mühle, A Neuner, J Park, F Pacho, Q Jiang, S Waddington, H Schneider
ZeitschriftZeitschrift für Geburtshilfe und Neonatologie
Ausgabe05/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: Prenatal gene therapy has been considered for diseases such as Herlitz junctional epidermolysis bullosa (H-JEB), a lethal genodermatosis caused by absence of any of the three subunits of the basement membrane protein laminin-5. H-JEB presents from birth with widespread blistering of skin and mucosae and leads to death typically within the first year of life. In this study, we investigated in a mouse mode…
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Zitierempfehlung
C Mühle, A Neuner, J Park, F Pacho, Q Jiang, S Waddington, H Schneider (2006) Evaluation of prenatal intra-amniotic LAMB3 gene delivery by adenoviral and AAV vectors in a mouse model of Herlitz junctional epidermolysis bullosa. Zeitschrift für Geburtshilfe und Neonatologie (05). https://doi.org/10.1055/s-2006-943291
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