CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The role of decorin in liver fibrogenesis
DOI 10.1055/s-2006-943370
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Autor:innenK Baghy, P Nagy, R Iozzo, S Thorgeirsson, I Kovalszky
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe06/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Accumulation of connective tissue is a typical feature of chronic liver diseases. TGF-β1 is one of the major stimulators of fibrogenesis; therefore, its neutralization is a principal aim in antifibrotic research. Decorin, a small ECM proteoglycan, is capable of regulating connective tissue proliferation by blocking the maturation of collagen fibrils, and by inhibiting TGF-β1. To better understand the r…
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Zitierempfehlung
K Baghy, P Nagy, R Iozzo, S Thorgeirsson, I Kovalszky (2006) The role of decorin in liver fibrogenesis. Zeitschrift für Gastroenterologie (06). https://doi.org/10.1055/s-2006-943370
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