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Different transforming growth factor-B1 induces extracellular matrix production in rat hepatic stellate cells versus hepatic myofibroblasts, but decorin inhibits both

G Firneisz, J Dudás, T Szarvas, E Sári, G Ramadori, I Kovalszky · Zeitschrift für Gastroenterologie · Ausgabe 06/2006

DOI 10.1055/s-2006-943392

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Autor:innenG Firneisz, J Dudás, T Szarvas, E Sári, G Ramadori, I Kovalszky
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe06/2006
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

The main pathological feature that leads to human liver disease is the deposition and accumulation of the extracellular matrix (ECM). Different stimuli might cause liver damage, but the hepatic stellate cells (HSC) are thought to primarily produce the accumulating ECM proteins and in many pathologic conditions the transforming growth factor-B1 has a crucial role. Decorin was reported to act as a natural inhibitory a…

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G Firneisz, J Dudás, T Szarvas, E Sári, G Ramadori, I Kovalszky (2006) Different transforming growth factor-B1 induces extracellular matrix production in rat hepatic stellate cells versus hepatic myofibroblasts, but decorin inhibits both. Zeitschrift für Gastroenterologie (06). https://doi.org/10.1055/s-2006-943392

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