CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The potential role of regulatory t cells and TGF-β1 in downregulating NKG2D killer activator receptor expression on cytotoxic cells in patients with chronic HCV hepatitis
DOI 10.1055/s-2006-943458
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Nachweis in CareLit
Autor:innenG Pár, T Berki, L Pálinkás, L Szereday, M Halász, A Miseta, G Hegedűs, Z Faust, G Mózsik, B Hunyady, A Pár
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe06/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Impaired natural killer (NK) cell activity has been proposed to contribute to viral persistence in HCV infection. Recent studies demonstrated that in tumors regulatory T cells (Treg) the secreted TGFβ1 down-regulates NKG2D killer activator receptor and NK cytotoxicity. Since in chronic hepatitis C plasma TGFβ1 level is also increased, we analyzed whether decreased NK activity corresponds to a dysregulated expr…
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Zitierempfehlung
G Pár, T Berki, L Pálinkás, L Szereday, M Halász, A Miseta, G Hegedűs, Z Faust, G Mózsik, B Hunyady, A Pár (2006) The potential role of regulatory t cells and TGF-β1 in downregulating NKG2D killer activator receptor expression on cytotoxic cells in patients with chronic HCV hepatitis. Zeitschrift für Gastroenterologie (06). https://doi.org/10.1055/s-2006-943458
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