CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Proteinase-activated receptor-2 agonist induced visceral hyperalgesia is prevented by dexamethasone via regulation of colonic mast cells in rats
DOI 10.1055/s-2006-943473
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Autor:innenR Róka, A Ait-Belgnoui, J Fioramonti, L Bueno, T Wittmann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe06/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Low-grade inflammation may play a role in the pathogenesis of irritable bowel syndrome. The aim of this study was to evaluate if dexamethasone (DEX) treatment prevents proteinase-activated receptor-2 (PAR-2) activation induced visceral hyperalgesia in rats, and to determine the role of PAR-2 and colonic mast cells in the effect of corticosteroid therapy. Methods: Abdominal contractions provoked by rectal distension…
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Zitierempfehlung
R Róka, A Ait-Belgnoui, J Fioramonti, L Bueno, T Wittmann (2006) Proteinase-activated receptor-2 agonist induced visceral hyperalgesia is prevented by dexamethasone via regulation of colonic mast cells in rats. Zeitschrift für Gastroenterologie (06). https://doi.org/10.1055/s-2006-943473
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