CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Rosiglitazone induced improvement of insulin sensitivity is mediated by tissue-specific changes of 11ß-HSD1 activity
DOI 10.1055/s-2006-943762
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Mai, T Bobbert, J Andres, C Maser-Gluth, AF Pfeiffer, S Diederich, J Spranger
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe06/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: The insulin sensitising effect of the PPARγ agonist rosiglitazone (R) is comparable to the effect of a reduction in 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) activity in animal models. However it is unclear, whether the R-induced insulin sensitivity is associated with a decrease in 11β-HSD1 activity in different tissues. We therefore aimed to investigate the tissue-specific effects of R on 11β…
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Zitierempfehlung
K Mai, T Bobbert, J Andres, C Maser-Gluth, AF Pfeiffer, S Diederich, J Spranger (2006) Rosiglitazone induced improvement of insulin sensitivity is mediated by tissue-specific changes of 11ß-HSD1 activity. Diabetologie und Stoffwechsel (06). https://doi.org/10.1055/s-2006-943762
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