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Krueppel-like transcription factor 11 (KLF11) inhibits activity of the human proinsulin promoter in pancreatic beta-cells

X Niu, G Päth, C Limbert, MD Brendel, RG Bretzel, J Seufert · Diabetologie und Stoffwechsel · Ausgabe 06/2006

DOI 10.1055/s-2006-943768

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Autor:innenX Niu, G Päth, C Limbert, MD Brendel, RG Bretzel, J Seufert
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe06/2006
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

KLF11 (TIEG2) is a member of the Sp1/KLF transcription factor family which plays an important role in mammalian gene regulation. KLF11 is a pancreas-enriched transcription factor that has elicited significant attention because of its role as negative regulator of exocrine cell growth in vitro and in vivo. However, its functional role in the endocrine pancreas remains to be established. Here we investigated endogenou…

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Zitierempfehlung

X Niu, G Päth, C Limbert, MD Brendel, RG Bretzel, J Seufert (2006) Krueppel-like transcription factor 11 (KLF11) inhibits activity of the human proinsulin promoter in pancreatic beta-cells. Diabetologie und Stoffwechsel (06). https://doi.org/10.1055/s-2006-943768

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