CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Selective ablation of hypothalamic POMC-expressing neurons leads to hyperphagia and weight gain
DOI 10.1055/s-2006-943787
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Autor:innenE Rother, T Buch, JC Brüning
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe06/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The pro-opiomelanocortin (POMC) gene is expressed in a subset of hypothalamic and hindbrain neurons and in pituitary melanotrophs and corticotrophs. POMC neurons in the arcuate nucleus (ARC) of the hypothalamus have been shown to play an important role in the regulation of energy homeostasis by integrating peripheral hormonal signals such as Leptin and Insulin in order to promote negative energy balance. As expected…
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Zitierempfehlung
E Rother, T Buch, JC Brüning (2006) Selective ablation of hypothalamic POMC-expressing neurons leads to hyperphagia and weight gain. Diabetologie und Stoffwechsel (06). https://doi.org/10.1055/s-2006-943787
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