CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Sp1 O-glycosylation leads to glucose-dependent NF-κBp65 activation
DOI 10.1055/s-2006-943810
Bibliografische Angaben
Nachweis in CareLit
Autor:innenY Seregin, O Voron'ko, Z Djuric, PM Humpert, G Rudofsky, I Konrade, M Morcos, PP Nawroth, A Bierhaus
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe06/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: The transcription factor NF-κB plays an important role in diabetes. The molecular mechanisms underlying the observed long-term activation of NF-κB p65 mRNA transcription in diabetes are yet unknown. Characteristics of the p65 promoter shows three binding sites for the transcription factors Sp1/Sp3, implying that these proteins might act as transactivators of p65 de novo synthesis under hyperglycemic co…
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Zitierempfehlung
Y Seregin, O Voron'ko, Z Djuric, PM Humpert, G Rudofsky, I Konrade, M Morcos, PP Nawroth, A Bierhaus (2006) Sp1 O-glycosylation leads to glucose-dependent NF-κBp65 activation. Diabetologie und Stoffwechsel (06). https://doi.org/10.1055/s-2006-943810
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