CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Deletion of protein kinase C beta does not protect against the development of albuminuria in streptozotocin-induced experimental murine diabetic nephropathy
DOI 10.1055/s-2006-943836
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Meier, J Menne, JK Park, O Daniel, C Lindschau, M Leitges, H Haller
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe06/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
PKC activation is a key factor in the development of diabetic microangiopathy. Deletion of the classical PKC-isoform-alpha e.g. protects against the development of albuminuria due to a diminished loss of proteoglycans whereas increased TGF-beta1 and renal hypertrophy is not prevented. We now tested the hypothesis that deletion of PKC-beta-expression, another classical PKC isoform which has been involved in diabetic…
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Zitierempfehlung
M Meier, J Menne, JK Park, O Daniel, C Lindschau, M Leitges, H Haller (2006) Deletion of protein kinase C beta does not protect against the development of albuminuria in streptozotocin-induced experimental murine diabetic nephropathy. Diabetologie und Stoffwechsel (06). https://doi.org/10.1055/s-2006-943836
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