CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
RAGE modulates neuronal glyoxalase-1 transcription, expression and activity
DOI 10.1055/s-2006-943839
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Autor:innenSB Stoyanov, GM Haag, I Konrade, IK Lukic, P Humpert, P Thornalley, SR Thorpe, PP Nawroth, A Bierhaus
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe06/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Methylglyoxal (MG) is a precursor of a variety of advanced glycation endproducts (AGEs), which are supposed to contribute to the development of late diabetic complications via interaction with their cellular receptor RAGE. MG and other AGE-precursors are detoxified by the glyoxalase-system. Aim: We study expression of the AGE-detoxifying enzyme glyoxalase-1 (GO-1) in peripheral nerves and dorsal root g…
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Zitierempfehlung
SB Stoyanov, GM Haag, I Konrade, IK Lukic, P Humpert, P Thornalley, SR Thorpe, PP Nawroth, A Bierhaus (2006) RAGE modulates neuronal glyoxalase-1 transcription, expression and activity. Diabetologie und Stoffwechsel (06). https://doi.org/10.1055/s-2006-943839
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