CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Haplotypes in the insulin-degrading enzyme gene are associated with enhanced insulin clearance in non-diabetic subjects
DOI 10.1055/s-2006-943964
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Nachweis in CareLit
Autor:innenO Pivovarova, M Osterhoff, M Möhlig, J Spranger, P Slominski, S Limborsky, AFH Pfeiffer, N Rudovich
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe06/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Insulin-degrading enzyme (IDE) is the major enzyme responsible for insulin proteolysis and is encoded by the IDE gene, which is located on chromosome 10q23-q24 within a region linked to T2DM. The aim of this study was to investigate whether genetic variants of the IDE-gene play a role in the regulation of insulin clearance in humans. Methods: We screened 10 SNP's in the IDE gene and determined their associatio…
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Zitierempfehlung
O Pivovarova, M Osterhoff, M Möhlig, J Spranger, P Slominski, S Limborsky, AFH Pfeiffer, N Rudovich (2006) Haplotypes in the insulin-degrading enzyme gene are associated with enhanced insulin clearance in non-diabetic subjects. Diabetologie und Stoffwechsel (06). https://doi.org/10.1055/s-2006-943964
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