CareLit · DOI-Nachweis · Zeitschrift für Geburtshilfe und Neonatologie
Buffering Acidosis during Permissive Hypercapnia to Restore Physiologic PH May Increase the Degree of Lung Injury in Surfactant Deficient Rabbits
DOI 10.1055/s-2006-946072
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Autor:innenHD Hummler, A Engelmann, A Merinsky, S Häring, AR Franz, M Ebsen, MR Wolfson, F Pohlandt
ZeitschriftZeitschrift für Geburtshilfe und Neonatologie
Ausgabe11/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Buffering hypercapnic acidosis is commonly performed in the ICU when patients with respiratory failure are exposed to permissive hypercapnia. Objective: To study the hypothesis that buffering hypercapnic acidosis worsens the degree of lung injury in an animal model of surfactant deficiency. Methods: 28 anesthetized, surfactant-depleted rabbits were mechanically ventilated with an FiO2=1.0, Vt=4.5ml/kg, P…
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Zitierempfehlung
HD Hummler, A Engelmann, A Merinsky, S Häring, AR Franz, M Ebsen, MR Wolfson, F Pohlandt (2006) Buffering Acidosis during Permissive Hypercapnia to Restore Physiologic PH May Increase the Degree of Lung Injury in Surfactant Deficient Rabbits. Zeitschrift für Geburtshilfe und Neonatologie (11). https://doi.org/10.1055/s-2006-946072
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