CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Endocytic pathways of luminal antigens intersect MHC class I and class II pathways in multivesicular late endosomes – Antigen trafficking in intestinal epithelial cells studied in vivo in Crohn's disease patients
DOI 10.1055/s-2006-950626
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Autor:innenG Hundorfean, S Strobel, KP Zimmer, A Gebert, D Ludwig, J Büning
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aims: In Crohn's disease (CD), intestinal epithelial cells (IEC) are suggested to be involved in the stimulation of pro-inflammatory CD4+ and CD8+ T cells. The underlying mechanisms of MHC class I and class II-associated presentation of exogenous antigens by IEC remain unknown. Here we investigate the subcellular expression of MHC class I and class II in IEC and it's interference with the endocytic tr…
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Zitierempfehlung
G Hundorfean, S Strobel, KP Zimmer, A Gebert, D Ludwig, J Büning (2006) Endocytic pathways of luminal antigens intersect MHC class I and class II pathways in multivesicular late endosomes – Antigen trafficking in intestinal epithelial cells studied in vivo in Crohn's disease patients. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2006-950626
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