CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Conversion of human CD4+CD25-FOXP3- into CD4+CD25+FOXP3+ T cells: Implications for a cell-based therapy for IBD?
DOI 10.1055/s-2006-950675
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Autor:innenJ Maul, K Büchner, A Wenzel, M Zeitz, R Duchmann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Regulatory CD4+CD25+FOXP3+ T cells (Treg) prevent and treat established colitis in animal models and they are numerically deficient in patients with active IBD. This suggests that cellular Treg therapy might be a promising option. Autologous Treg for cellular therapy might be obtained by in vitro expansion of natural Treg or conversion of CD4+CD25-FOXP3- cells into functional Treg. Aim: Since the isolation of…
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Zitierempfehlung
J Maul, K Büchner, A Wenzel, M Zeitz, R Duchmann (2006) Conversion of human CD4+CD25-FOXP3- into CD4+CD25+FOXP3+ T cells: Implications for a cell-based therapy for IBD?. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2006-950675
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