CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Differential effects of PDZ-Adapterprotein NHERF1, E3KARP and PDZK1 knockout on the regulation of NHE3 transport activity in native murine colonic epithelium
DOI 10.1055/s-2006-950687
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Autor:innenA Cinar, M Chen, B Riederer, B Hogema, H de Jonge, M Donowitz, EJ Weinman, O Kocher, U Seidler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background & Aims: The PDZ-adapter proteins NHERF1, E3KARP and PDZK1 have all been shown to bind to the sodium hydrogen exchanger NHE3, and to be expressed in the brush border membrane (BBM) of murine intestine. In PS120 fibroblasts, NHERF1 or E3KARP coexpression with NHE3 is required for cAMP-mediated inhibition of NHE3 trans-port activity. We therefore investigated, whether the three NHE3 binding PDZ-proteins show…
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Zitierempfehlung
A Cinar, M Chen, B Riederer, B Hogema, H de Jonge, M Donowitz, EJ Weinman, O Kocher, U Seidler (2006) Differential effects of PDZ-Adapterprotein NHERF1, E3KARP and PDZK1 knockout on the regulation of NHE3 transport activity in native murine colonic epithelium. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2006-950687
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