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Evaluation of cross-genotype immunity by multigenotype HCV-NS3 recombinant vaccinia virus surrogat infection

C Eisenbach, A Freyse, C Lupu, K Weigand, E Ernst, B Hoyler, W Stremmel, J Bugert, J Encke · Zeitschrift für Gastroenterologie · Ausgabe 09/2006

DOI 10.1055/s-2006-950779

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Autor:innenC Eisenbach, A Freyse, C Lupu, K Weigand, E Ernst, B Hoyler, W Stremmel, J Bugert, J Encke
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben

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Aims: The development of an effective prophylactic vaccine against the hepatitis C virus (HCV) remains a major problem despite considerable efforts. Progress has been hampered by the lack of a convenient animal model and until recently by the limitations in growing the virus in cell culture. Therefore, experimental vaccines are frequently tested in mice, often employing HLA-A2.1 transgenic strains. Surrogate infecti…

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C Eisenbach, A Freyse, C Lupu, K Weigand, E Ernst, B Hoyler, W Stremmel, J Bugert, J Encke (2006) Evaluation of cross-genotype immunity by multigenotype HCV-NS3 recombinant vaccinia virus surrogat infection. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2006-950779

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