CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
In hepatocytes TGF-β induces Epithelial-to-Mesenchymal Transition (EMT)
DOI 10.1055/s-2006-950781
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Autor:innenH Gaitantzi, L Ciuclan, P Godoy, MV Singer, S Dooley, K Breitkopf
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Chronic intoxication of the liver with alcohol or hepatotoxic viruses is known to induce liver fibrosis which progresses to cirrhosis or hepatocellular carcinoma. During fibrogenesis liver cells, especially activated hepatic stellate cells (HSCs) release the pro-fibrogenic cytokine TGF-β and we have previously shown that general hepatic overexpression of the TGF-β antagonist Smad7 abrogates development…
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Zitierempfehlung
H Gaitantzi, L Ciuclan, P Godoy, MV Singer, S Dooley, K Breitkopf (2006) In hepatocytes TGF-β induces Epithelial-to-Mesenchymal Transition (EMT). Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2006-950781
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