CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Interleukin-10 and TGF-β are potent regulators of the transcriptional and antiviral response of IFN-α in non-parenchymal liver cells
DOI 10.1055/s-2006-950791
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Autor:innenJ Wu, P Grünewald, M Lu, M Trippler, G Gerken, J Schlaak
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: IFN-α plays an important role in the defense against most viruses and is used for the treatment of hepatotropic viruses (HCV, HBV). However, there is still only little known about the specificity of the IFN-α response in non-parenchymal liver cells and its regulation by anti-inflammatory cytokines. Methods: To address these questions murine Kupffer cells (KC) and sinusoidal endothelial cells (LSEC) were isolat…
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Zitierempfehlung
J Wu, P Grünewald, M Lu, M Trippler, G Gerken, J Schlaak (2006) Interleukin-10 and TGF-β are potent regulators of the transcriptional and antiviral response of IFN-α in non-parenchymal liver cells. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2006-950791
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