CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Tauroursodeoxycholic acid shows converse effects on TGF-β-Smad 3 signaling in liver cells
DOI 10.1055/s-2006-950796
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Autor:innenL Wickert, N Chatain, K Kruschinsky, AM Gressner
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Tauroursodeoxycholic acid (TUDCA) has a positive effect on cholestatic liver disease especially with autoimmune etiology, which seems to be further enhanced by a combination with locally active corticosteroids. TGF-β, a master cytokine of liver fibrosis, activates hepatic stellate cells (HSC) and induces extracellular matrix components in vivo and in vitro. Our recent studies with HSC showed that glucocorticoi…
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Zitierempfehlung
L Wickert, N Chatain, K Kruschinsky, AM Gressner (2006) Tauroursodeoxycholic acid shows converse effects on TGF-β-Smad 3 signaling in liver cells. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2006-950796
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