CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Characterization of the TGF-β antagonistic properties of Ski, SnoN and Smad7 in primary mouse hepatocytes
DOI 10.1055/s-2006-950800
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Autor:innenL Ciuclan, P Godoy, VM Singer, S Dooley, K Breitkopf
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
TGF-β is a profibrotic cytokine that plays a central role in the progression of chronic liver diseases. Since hepatocytes are the predominant liver cell type and are clearly responsive to TGF-β, they may also contribute to fibrogenesis. TGF-β activity is tightly controlled by multiple mechanisms, including antagonism of Smad activities by different co-repressors. Aims: To study the TGF-β pathway in mouse hepatocytes…
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Zitierempfehlung
L Ciuclan, P Godoy, VM Singer, S Dooley, K Breitkopf (2006) Characterization of the TGF-β antagonistic properties of Ski, SnoN and Smad7 in primary mouse hepatocytes. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2006-950800
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